- Do donors need to be matched to a diseased sample set? If so, how closely? Age? (plus/minus 5 years?) Gender? Comorbidities? Treatments?
- Is Type II diabetes a problem?
- Other inflammatory diseases?
- A known history of cancer?
- Other, concurrent cancers or related diseases to that which you are studying?
- Smoking?
- Alcohol consumption?
- What about medications that many older donors may be on (if relevant), such as statins or blood pressure medications?
- How much data do you need?
- How long can you wait for your samples? (The more criteria you have, the longer it will take to find acceptable donors.)
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