Papillary urothelial carcinoma, urothelial carcinoma (including transition cell, with endophytic growth pattern. with squamous or glandular differentiation, with focal squamous), adenocarcinoma mucinous, squamous metaplasia, urothelial dysplasia, Carcinoma in situ, Micropapillary carcinoma metastatic, Papillary urothelial neoplasm of low malignant potential (PUNLMP), Squamous cell carcinoma
Papillary urothelial carcinoma, urothelial carcinoma (including transition cell, with endophytic growth pattern. with squamous or glandular differentiation, with focal squamous), adenocarcinoma mucinous, squamous metaplasia, urothelial dysplasia, Carcinoma in situ, Micropapillary carcinoma metastatic, Papillary urothelial neoplasm of low malignant potential (PUNLMP), Squamous cell carcinoma
Malignant glioma, Glioblastoma multiforme (GBM), Glioblastoma, Fibrillary astrocytoma samples, Fibrillary astrocytoma with gemistocytic features, Pilocytic astrocytoma, Oligodendroglioma, Anaplastic astrocytoma, meningioma (psammomatous, fibrous, angiomatous, transitional and secretory types),Angiomatous meningioma, Atypical glial proliferation with Rosenthal fibers, B-cell lymphoma in brain, Hemangioma, fibrous tumor (hemangiopericytoma), Chordoid meningioma, Craniopharyngioma adamantinomatous, Desmoplastic/nodular medulloblastoma, Ependymoma, Ganglioglioma, Gliosarcoma, Gliosis, Hemangioblastoma, small cell glioblastoma, gliomatosis cerebri, Low grade neuroglial lesion, Myxoid glioma, Pineocytoma, Pituitary adenoma, microcystic glioma,Subependymal giant cell astrocytoma, Subependymoma, Myxopapillary ependymoma,Spinal cord tumor, Paraganglioma
Invasive & non-invasive ductal (Ductal Carcinoma In Situ, DCIS) and lobular, BRCA1/2 positive/negative, Benign breast therapy related changes, benign breast, Adenocarcinoma, phyllodes tumor, duct ectasia, apocrine metaplasia, Cribriform carcinoma, Ductal Adenocarcinoma with Apocrine, squamous differentiation), Focal atypical lobular hyperplasia, Lobular carcinoma signet ring cell type, Papillary carcinoma, ADH, ALH, Spindle cell carcinoma
Adenocarcinoma (/ with mucinous features), Carcinoid, Malignant mesothelioma epithielioid type, Signet ring cell carcinoma, Tubular adenoma, Tubulovillous adenoma with focal high grade dsyplasia, Metastatic mucinous colorectal adenocarcinoma, Colonic sessile serrated and hyperplastic polyps, Ulcerative Colitis with pseudopolyps, Adipose tissue with nodules of fat necrosis with embedded suture type material- negative for carcinoma, B cell lymphoma, Appendix, Ileocecal submucosal lipoma, Hyperplastic polyps, Leiomyoma, Low grade appendiceal mucinous neoplasm, Malignant mesothelioma -epithielioid type, Malignant mixed (epithelioid and spindle cell) gastrointestinal stromal tumor (GIST), Mantle cell lymphoma forming colonic massesand involving lymph nodes, Metastatic squamous cell carcinoma, Mixed adenoneuroendocrine carcinoma, mixed goblet cell carcinoid-adenocarcinoma, Papilliary serous carcinoma, Pleomorphic undifferentiated sarcorma with prominent inflammation, submucosal lipoma
Adenocarcarinoma (endometrial, mullerian, endometrioid, chondroid, squamous, mucinous, serous, clear cell, signet ring, villoglandular), Adenomyosis, Endometriosis, leiomyomata, vascular leiomyoma, Atypical endometrial hyperplasia, Benign ecto/endocervix with nabothian cysts, Benign endometrial polyps, Benign hemorrhagic cyst, Benign serous cystadenoma, benign leiomyoma, Carcinosacoma, Cear cell carcinoma, large cell neuroendocrine carcinoma, Complex atypical hyperplasia, Embryonal rhabdomyosarcoma, Endocervical adenocarcinoma in-situ, clear cell carcinoma of endocervix, Endometrioma, Lipoma, Intravascular leiomyomatosis, lobular carcinoma, Polypoid adenomyoma, Small cell neuroendocrine carcinoma, Squamous metaplasia, mesonephric carcinoma (rare), Available from clinical and post mortem donors, except for Cervical cancer: post mortem only (fresh, frozen or NBF).
Adenocarcinoma – intestinal type/ Lauren classification / Diffuse type/ Signet ring cell type, Gastric schwannoma, gastrointestinal stromal tumor (GIST),GIST spindle cell, Neuroendocrine, Esophageal cancer,
Hepatic Adenoma,Adenocarcinoma – , Adenosquamous carcinoma, Incidental bile duct adenoma, Gall bladder cancer, Focal nodular hyperplasia, Hepatocellular carcinoma (HCC) – clear cell and pleomorphic types, Inflammatory pseudotumor, Intrahepatic cholangiocarcinoma, ampullary carcinoma/ Carcinoma of the Ampulla of Vater, Spleen – B-cell lymphoma, consistent with follicular lymphoma.
Usually post mortem only Mostly post mortem (fresh, frozen or NBF)
Adrenal cortical adenoma, Adrenal cortical carcinoma, Angiomyolipoma, Benign renal cortical cyst, Chromophobe renal cell carcinoma, Clear cell renal carcinoma – with sarcomatoid features/ cystic change/ multilocular features, carcinoma, Clear cell papillary renal cell carcinoma, Cystic clear cell carcinoma, Epithelioid angiomyolipoma, Oncocytoma, Papillary adenoma, Papillary carcinoma, Pheochromocytoma, Renal adenomatosis, Renal cell carcinoma – with eosinophilic features, Renal epithelial neoplasm, Chronic ureteritis with nodular lymphoid hyperplasia and papillary urothelial hyperplasia
Adenocarcinoma (acinar, solid, lepidic, with mucinous features, micropapillary patterns, with focal signet ring cell features), Adenosquamous carcinoma, Atypical carcinoid tumor with spindle cell features, Carcinoid, Solitary Fibrous tumor, Large cell neuroendocrine carcinoma, Multiple carcinoid tumorlets, Pulmonary hamartoma (chondromatous), Reactive follicular hyperplasia and anthracosis with associated histiocytic reaction – negative for malignancy, Sarcomatoid spindle cell squamous cell carcinoma, Non-Small Cell Lung Carcinoma (NSCLC), Small cell lung carcinoma (SCLC), Squamous cell carcinoma, Neuroendocrine tumor
Human hematologic malignancies, such as lymphomas, leukemias and myeloma, including CLL, AML, Hodgkin’s Lymphoma, Hairy cell leukemia, MDS, Acute Moncytic Lymphoma, B-cell lymphoma, T-cell lymphoma, Burkitt Lymphoma, DLBCL, Non Hodgkin Lymphoma, and Multiple Myeloma are available as fresh peripheral blood, fresh bone marrow, or as frozen or FFPE bone marrow aspirate or core specimens (trephine biopsies) from the hospitals and pathology service providers we work with. Lymph node samples, as well as lymphoma tumors from other organs, may also be available.
Plasma, serum, buffy coat or whole blood may also be available from our clinical biobank sites.
Deceased donor bone marrow and lymph node specimens, offering large quantities of material, can also be collected prospectively. Preliminary feedback from fresh bone marrow specimens we have provided indicates high levels of viability- please inquire. Material can also be provided frozen, snap-frozen or fixed in 10% NBF.
Many tumor types, many sites; clinical and post mortem donors.
Adenocarcinoma (endometrioid, mucinous, serous, clear cell), benign Brenner’s tumor (very rare), Benign rete cyst with mural hilar cell proliferation, Benign endometrila polyps in a background of cystic atrophy, Benign ovarian serous cystadenofibroma, Benign hemorrhagic cyst, Benign serous cyst, Benign serous cystadenofibroma with dystrophic calcifications, Carcinosarcoma, Cellular Fibroma, Endosalpingiosis, Endometrioma, Sex cord stromal tumor, Granulosa/Granulosa-theca cell tumor, Leiomyoma, Mixed germ cell tumor, Neuroendocrine, Papillary serous carcinoma with psammomatous calcifications, Small cell carcinoma – hypercalcemic type, Teratoma
Acinar cell carcinoma, Adenocarcinoma (ductal, mucinous, squamous differentiation), Adenocarcinoma arising in association with Intraductal papillary mucinous neoplasm of pancreas (IPMN), Hyperplastic ampullary epithelium with acute inflammation and reactive cellular changes, Incidental low grade pancreatic intraepithelial neoplasia, Mucinous cystic neoplasm, with low and focal intermediate dysplasia, Neuroendocrine carcinoma, Insulinoma, Retroperitoneal cyst of Mullerian type with focal adenocarcinoma, Serous cysta adenoma, microcystic type, Solid pseudopapillary neoplasm, Undifferentiated carcinoma with osteoclast-like giant cells
Adenocarcinoma, Serous adenocarcinoma, Ganglioneuroma, appendiceal mucinous neoplasm, Mesothelioma, Neurofibroma, Sebaceous carcinoma, Liposarcoma, Papillary mesothelioma
Post mortem (fresh, frozen or NBF) or clinical: FFPE or frozen, including castration-resistant.
Clinical: mostly metastatic sites: FFPE & frozen, with biomarker data. Post mortem: available fresh, frozen or in 10% NBF, primary & metastases.
Adenomatoid tumor, Classic / seminoma, Malignant germ cell tumor, Malignant mixed germ cell tumor, Teratoma, Yolk sac tumor, Choriocarcinoma, Embyonal carcinoma, Intratubular germ cell neoplasia, Sertoli cell tumor (NOS)
Mostly post mortem (fresh, frozen or NBF)